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Home > Products >  Doxorubicin hydrochloride 25316-40-9

Doxorubicin hydrochloride 25316-40-9 CAS NO.25316-40-9

  • FOB Price: USD: 2,000.00-2,000.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Available Specifications:

    Medical grade(1-5)Kilogram

  • Product Details

Keywords

  • Doxorubicin hydrochloride
  • Doxorubicin hcl
  • 25316-40-9

Quick Details

  • ProName: Doxorubicin hydrochloride 25316-40-9
  • CasNo: 25316-40-9
  • Molecular Formula: C27H29NO11.HCL
  • Appearance: Orange-red crystalline powder or amorp...
  • Application: API
  • DeliveryTime: within one week
  • PackAge: 25kgs/drum paper-drums and two plastic...
  • Port: Shanghai
  • ProductionCapacity: 100 Kilogram/Week
  • Purity: 98.0%~102.0%
  • Storage: Store in tight containers, in a cool d...
  • Transportation: Express(DHL/FedEx/TNT),AIR,SEA
  • LimitNum: 1 Kilogram
  • Related Substances: Daunorubicin ≤0.5%Daunorubicinone ≤0.5...
  • Residue on Ignition: Meets the requirements
  • Heavy Metal: ≤10 ppm
  • Valid Period: 2 years when properly stored
  • Boiling Point: 810.3 °C at 760 mmHg
  • Melting Point: 216°C
  • Flash Point: 443.8 °C

Superiority

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many years, with own laboratories and GMP standard factories.

1. 12 years specialized in health products field.
2. GMP/ISO certificated factories and stable supply chain.
3. Quality first, strictly control before shipments.
4. Custom synthesis by more than 20 professional chemists.
5. Small order,free sample and one step service available.
6. Rapid delivery, 1-6 business days from China warehouse.
7. Support 7 days refund money in case delay shipment.
8. Assessment conducted by Bureau Veritas at 2018.

Details

【Product name】 Doxorubicin Hydrochloride
【Synonyms】 5,12-Naphthacenedione; Adriamycin hydrochloride (8CI); ADM hydrochloride; ADR; Adriablastina CS; Adriacin; Adriamycin; Adriblastin; Adriblastina; Adriblastina RD; DOX HCl; FI 106; FI 6804; Lipo-Dox;

【Appearance】 Orange-red crystalline powder or amorphous particles
【CAS No.】 25316-40-9
【Molecular Formula】 C27H29NO11.HCL
【Molecular Weight】 579.99
【Assay】 98.0%~102.0%
【Quality Standard】 USP39 pharm.grade
【Packing Size】 1kg /Bottle, 5KGS /DRUM, 10KGS /DRUM
【Storage】 Tight container, protect from light and low temperature( 2-8°C).

Doxorubicin hydrochloride, also name Hydroxydaunorubicin hydrochloride, is a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is an effective human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively, Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.

Quality Standard

Items

Specification

Assay (Anhydrous) 

98.0%~102.0% (C27H29NO11.HCL)

Appearance

Orange-red crystalline powder or amorphous particles

Identification (HPLC)

The retention time of the doxorubicin peak of the sample solution corresponds to that of the standard solution, as obtained in the assay.

pH

4.0~5.5

Related Substances

 

 

Daunorubicin ≤0.5%

Daunorubicinone ≤0.5%

Doxorubicinone ≤0.5%

Water content

≤4.0%

Residual Solvents

 

 

 

 

 

 

Any other impurity ≤0.5%

Total impurities ≤2.0%

Methanol ≤3000ppm

Ethanol ≤10000ppm

Acetone ≤5000ppm

Dichloromethane ≤600ppm

Dioxane ≤380ppm

 

Function

Doxorubicin hydrochloride is used to produce regression in disseminated neoplastic conditions like acute lymphoblastic leukemia, acute myeloblastic leukemia, neuroblastoma, wilms’ tumor, soft tissue and bone sarcomas, ovarian carcinoma, breast carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, Hodgkin’s disease, gastric carcinoma, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types. 

Doxorubicin hydrochloride can also indicated for use as a component of adjuvant therapy for women with evidence of axillary lymph node involvement following resection of primary breast cancer.
 

Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.

Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments. 

Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.

Company name

Shanghai Soyoung Biotechnology Inc.

Main Products

Health care ingredients

Location

Shanghai,China

Business Type

Manufacturer & Trader 

Year start exporting

2011

Number of employees

60-70 people

Factory area

18,000 square meters

Total annual output

180-220 tons

Main Markets

America,Europe,Mid East,Asia,South Africa and etc.

Certifications

GMP,ISO,HACCP,Kosher

 

We warmly welcome customers from at home and abroad to establish cooperation and create a bright future with us together. And leading the way to make health industries heathier, help more people healthy and happy…

 

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