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L-5-Methyltetrahydrofolate calcium 151533-22-1 levomefolate calcium 1 methylfolate CAS NO.151533-22-1
- FOB Price: USD: 2,250.00-2,250.00 /Kilogram Get Latest Price
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,MoneyGram
- Available Specifications:
Medical grade(1-5)Kilogram
- Product Details
Keywords
- L-5-Methyltetrahydrofolate calcium
- 1 methylfolate
- levomefolate calcium
Quick Details
- ProName: L-5-Methyltetrahydrofolate calcium 151...
- CasNo: 151533-22-1
- Molecular Formula: C20H23N7O6.Ca
- Appearance: White or light yellow crystalline powd...
- Application: Dietary supplement (L-5-Methyltetrahyd...
- DeliveryTime: deliver 2-5 days after confirmed order...
- PackAge: double bags,cartons,drums,according to...
- Port: any port of China
- ProductionCapacity: 2000 Kilogram/Month
- Purity: 97.5%~102.0%
- Storage: stored in sealed containers,cool dry p...
- Transportation: Express(DHL/FedEx/TNT/EMS)AIR,SEA
- LimitNum: 10 Gram
- Heavy Metal: ≤20ppm
- Limited Quantity: 1 KG
- Valid Period: 2 years when properly stored
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Details
【Product name】 L-5-Methyltetrahydrofolate calcium
【Chemical names】 6s-5-methyltetrahydrofolate calcium; methyltetrahydrofolate calcium
【Appearance】 White or light yellow crystalline powder
【CAS No.】 151533-22-1
【Molecular Formula】 C10H17N3O6S
【Molecular Weight】 497.52
【Assay】97.5%~102.0% (on dry basis) as Ca salt
【Quality Standard】 USP pharm. grade
【Packing Size】 5KGS /DRUM, 10KGS /DRUM, 25KGS /DRUM
【Storage】 Tight container, protect from light
L-5-methyltetrahydrofolate calcium, also called as 6s-5-methyltetrahydrofolate calcium; levomefolate calcium; L-5-MTHF-Ca; L-MTHF-Ca; L-MTHF. it is a synthetic derivative of folic acid, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization of L-5-MTHF as its calcium salt.
L-5-methyltetrahydrofolate calcium is a naturally occurring salt forming methyl derivative of folic acid, which is the most biologically active & functional folic acid form, it is more easily absorbed than ordinary folic acid, common folic acid must be converted to type I methyl folate in order to participate in two major metabolic pathways: methylation and DNA synthesis. and the form of free folate is 5-mthf normall present in human plasma and cells.
Quality standard
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Item |
Specifications |
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Appearance |
White or light yellow crystalline powder |
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Assay(on dry basis) as Ca salt |
97.5%~102.0% |
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Calcium content (on dry base) |
7.0%~8.5% |
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D-5-Methyltetrahydrofolate |
≤1.0% |
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Specific Rotation (no anhydrous substance) |
[a]25D(C=1.5% in water, 25℃) +38.0~ +45.0° |
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Identification |
HNMR |
HNMR should be identical with that of reference |
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HPLC |
The retention time of the major peak in the chromatograme of assay preparation corresponds to that in the chromatograme of the standard preparation, as obtained in the assay |
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Related Compounds |
Dimethyltetrahydrofolic acid ≤ 0.15% |
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Single impurity ≤ 1.0% |
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Total impurities ≤ 2.5% |
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Residual solvent |
Ethanol ≤5000ppm |
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Water content (KF) |
≤16.0% |
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Chloride (Cl) |
≤0.5% |
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Arsenic (As) |
≤1 ppm |
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Boron |
≤20 ppm |
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Heavy metals |
≤20 ppm (Pb ≤1 ppm, Cd ≤ 0.5 ppm, As ≤1.5 ppm, Hg ≤ 0.5 ppm) |
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Total plate count |
≤100 cfu/g |
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Total Yeast and Mold |
≤100 cfu/g |
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Salmonella |
Negative/25g |
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E. Coil |
Negative |
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Staphylococcus Aureus |
Negative |
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Function of L-5-Methyltetrahydrofolate calcium
1)L‐Methylfolate Calcium is a bioavailable source of folate.
2) As a dietary supplementation with folic acid or L-5-MTHF calcium are recommended to improve folate status and prevent adverse effects associated with folate deficiency.
3) L‐Methylfolate Calcium is safe under the proposed uses for infants and young children.
4) L‐Methylfolate Calcium has potential use in depression.
5) Our bodies need L‐methylfolate calcium to produce red blood cells. deficiency can lead to anemia or a low red blood cell count.
6) L‐Methylfolate Calcium plays a significant role during pregnancy because it prevents mothers keeping away from calcium deficiency while ensures infant grows healthly.
7) Other functions of L‐Methylfolate Calcium include repairing DNA, aiding and supporting immune functions, the body’s detoxification system, energy production and so on.
Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.
Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments.
Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.
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Company name |
Shanghai Soyoung Biotechnology Inc. |
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Main Products |
Health care ingredients |
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Location |
Shanghai,China |
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Business Type |
Manufacturer & Trader |
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Year start exporting |
2011 |
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Number of employees |
60-70 people |
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Factory area |
18,000 square meters |
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Total annual sales volume |
US$3,000,000-5,000,000 |
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Main Markets |
America,Europe,Mid East,Asia,South Africa and etc. |
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Certifications |
GMP,ISO,HACCP,Kosher |
Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many years, with own laboratories and GMP standard factories.
1. 12 years specialized in health products field.
2. GMP/ISO certificated factories and stable supply chain.
3. Quality first, strictly control before shipments.
4. Custom synthesis by more than 20 professional chemists.
5. Small order,free sample and one step service available.
6. Rapid delivery, 1-6 business days from China warehouse.
7. Support 7 days refund money in case delay shipment.
8. Assessment conducted by Bureau Veritas at 2018.