Doxorubicin hydrochloride 25316-40-9 CAS NO.25316-40-9
- FOB Price: USD: 2,000.00-2,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
Medical grade(1-5)Kilogram
- Product Details
Keywords
- Doxorubicin hydrochloride
- Doxorubicin hcl
- 25316-40-9
Quick Details
- ProName: Doxorubicin hydrochloride 25316-40-9
- CasNo: 25316-40-9
- Molecular Formula: C27H29NO11.HCL
- Appearance: Orange-red crystalline powder or amorp...
- Application: API
- DeliveryTime: within one week
- PackAge: 25kgs/drum paper-drums and two plastic...
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Week
- Purity: 98.0%~102.0%
- Storage: Store in tight containers, in a cool d...
- Transportation: Express(DHL/FedEx/TNT),AIR,SEA
- LimitNum: 1 Kilogram
- Related Substances: Daunorubicin ≤0.5%Daunorubicinone ≤0.5...
- Residue on Ignition: Meets the requirements
- Heavy Metal: ≤10 ppm
- Valid Period: 2 years when properly stored
- Boiling Point: 810.3 °C at 760 mmHg
- Melting Point: 216°C
- Flash Point: 443.8 °C
Superiority
Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many years, with own laboratories and GMP standard factories.
1. 12 years specialized in health products field.
2. GMP/ISO certificated factories and stable supply chain.
3. Quality first, strictly control before shipments.
4. Custom synthesis by more than 20 professional chemists.
5. Small order,free sample and one step service available.
6. Rapid delivery, 1-6 business days from China warehouse.
7. Support 7 days refund money in case delay shipment.
8. Assessment conducted by Bureau Veritas at 2018.
Details
【Product name】 Doxorubicin Hydrochloride
【Synonyms】 5,12-Naphthacenedione; Adriamycin hydrochloride (8CI); ADM hydrochloride; ADR; Adriablastina CS; Adriacin; Adriamycin; Adriblastin; Adriblastina; Adriblastina RD; DOX HCl; FI 106; FI 6804; Lipo-Dox;
【Appearance】 Orange-red crystalline powder or amorphous particles
【CAS No.】 25316-40-9
【Molecular Formula】 C27H29NO11.HCL
【Molecular Weight】 579.99
【Assay】 98.0%~102.0%
【Quality Standard】 USP39 pharm.grade
【Packing Size】 1kg /Bottle, 5KGS /DRUM, 10KGS /DRUM
【Storage】 Tight container, protect from light and low temperature( 2-8°C).
Doxorubicin hydrochloride, also name Hydroxydaunorubicin hydrochloride, is a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is an effective human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively, Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
Quality Standard
Items |
Specification |
Assay (Anhydrous) |
98.0%~102.0% (C27H29NO11.HCL) |
Appearance |
Orange-red crystalline powder or amorphous particles |
Identification (HPLC) |
The retention time of the doxorubicin peak of the sample solution corresponds to that of the standard solution, as obtained in the assay. |
pH |
4.0~5.5 |
Related Substances
|
Daunorubicin ≤0.5% |
Daunorubicinone ≤0.5% |
|
Doxorubicinone ≤0.5% |
|
Water content |
≤4.0% |
Residual Solvents
|
Any other impurity ≤0.5% |
Total impurities ≤2.0% |
|
Methanol ≤3000ppm |
|
Ethanol ≤10000ppm |
|
Acetone ≤5000ppm |
|
Dichloromethane ≤600ppm |
|
Dioxane ≤380ppm |
Function
Doxorubicin hydrochloride is used to produce regression in disseminated neoplastic conditions like acute lymphoblastic leukemia, acute myeloblastic leukemia, neuroblastoma, wilms’ tumor, soft tissue and bone sarcomas, ovarian carcinoma, breast carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, Hodgkin’s disease, gastric carcinoma, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types.
Doxorubicin hydrochloride can also indicated for use as a component of adjuvant therapy for women with evidence of axillary lymph node involvement following resection of primary breast cancer.
Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.
Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments.
Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.
Company name |
Shanghai Soyoung Biotechnology Inc. |
Main Products |
Health care ingredients |
Location |
Shanghai,China |
Business Type |
Manufacturer & Trader |
Year start exporting |
2011 |
Number of employees |
60-70 people |
Factory area |
18,000 square meters |
Total annual output |
180-220 tons |
Main Markets |
America,Europe,Mid East,Asia,South Africa and etc. |
Certifications |
GMP,ISO,HACCP,Kosher |
We warmly welcome customers from at home and abroad to establish cooperation and create a bright future with us together. And leading the way to make health industries heathier, help more people healthy and happy…